19 September 2018

29 biomarkers

Blood test reveals pancreatic cancer at an early stage

Svetlana Maslova, Hi-tech+

Pancreatic cancer is not the most common, but mortality from it is higher than from breast cancer. This type of tumor is extremely difficult to detect, but now scientists have developed a new laboratory test that will detect the disease at the earliest stage.

Pancreatic cancer is difficult to diagnose due to diffuse organ changes and is usually detected only at late stages of development. Now there is hope to rectify the situation: an international group of scientists led by researchers from Lund University (Sweden) has created a new laboratory blood test that detects pancreatic cancer in the early stages with 96% probability, writes EurekAlert.

The analysis reveals cancer at the first and second stages, when there is still a possibility of successful surgical intervention.

Currently, there is no effective treatment regimen for late-stage pancreatic cancer, when it is usually detected in a patient, so the new test has huge potential to reduce mortality.

The team selected 29 biomarkers from hundreds of others that most clearly detected the tumor.

As a result, the method makes it possible to detect the development of cancer long before it can be seen on CT scans.

In the future, the method is planned to be used to identify people with an increased risk of developing pancreatic cancer. These usually include people with genetic predispositions, patients with diabetes and chronic inflammatory diseases of the organ. To this end, a new clinical trial has already been launched, which should confirm the result.

Pancreatic cancer quickly forms metastases and reacts poorly to chemotherapy. However, researchers from the United States have developed a promising new drug: it inhibits the development of a tumor, acting at the genetic level.

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