05 July 2019

Without colonoscopy

A non-invasive test for intestinal diseases has been developed

Georgy Golovanov, Hi-tech+

A group of Polish researchers has proposed a new test for the painless detection of Crohn's disease and ulcerative colitis. Colonoscopy is not necessary, it is enough to study blood and stool samples.

The syndrome of increased intestinal permeability, also known as "leaky gut syndrome" is another indicator of digestive health, and it is often associated with inflammatory bowel diseases (IBD), which include Crohn's disease, ulcerative colitis and gluten–sensitive celiac disease, according to the report of The Physiological Society New, non-invasive test for bowel diseases.

Article by Jaworska et al. Inflammatory bowel disease associates with increased gut‐to‐blood penetration of SCFA: A new, noninvasive marker of a functional intestinal lesion published in the journal Experimental Physiology – VM.

According to the Lancet medical journal, these diseases haunt 0.3% of the population of Western countries, and spread as the world gradually Westernizes.

A study conducted by scientists from the Warsaw Medical University allows us to hope for an early diagnosis, which is extremely important in order to bring an incurable disease under control. Now IBD is difficult to diagnose, and the main methods – clinical symptoms and colonoscopy – are invasive, expensive and often require general anesthesia.

The method of Polish scientists is much simpler. Taking about 1 mm of blood and feces for analysis, doctors measure the ratio of short-chain fatty acids that bacteria secrete. It shows how well the barrier between the intestines and blood is functioning. When it is disturbed, undesirable elements – intestinal bacteria and their waste products – enter the bloodstream and cause diseases.

Scientists also hope that their method will be able to detect the presence of other diseases – liver problems or heart failure.

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