Antimicrobial mesh

The nanoset will deliver antibiotics exactly to the wound

Sergey Kolenov, N+1

The design, created by scientists from the two countries, is designed to treat surface injuries. The precise delivery of drugs ensures the destruction of dangerous bacteria and at the same time reduces the chances of their developing resistance.

Antibiotic resistance is one of the most serious problems of modern healthcare. Researchers from Flinders University together with colleagues from Japan. They have developed a special mesh of nanofibers for the delivery of two antibacterial drugs in the treatment of wounds.

As reported by Science Daily, the structure is a 20 by 15 cm mesh woven from 200 nm thick fibers. The hollow core of the fibers contains negatively charged gold nanoparticles, as well as the antibiotics colistin and vancomycin.

According to the authors' idea, the nanoset should slowly release the drugs directly into the area affected by bacteria. This reduces the concentration of antibiotics used without compromising effectiveness.

And accurate delivery guarantees that most bacteria will die before they have time to develop resistance.

Experiments on E. coli have confirmed that the design really effectively kills microorganisms. Now scientists have to understand how other types of nanoparticles affect the release of drugs. In addition, they intend to evaluate the possible side effects of using a nanoset and its stability during long-term storage.

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