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RNA against metastases
Modified regulatory RNA molecules sent to the tumor in nanoparticles discourage cancer cells from traveling.
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The results are so promising that the researchers plan to start clinical trials on cancer patients within a year.
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The growth and metastasis of tumors suppresses the inhibitor of autotaxin
In the new approach to the fight against cancer, the enzyme autotaxin is used as a pharmacological target – the culprit of the "vicious circle" of tumor growth, metastasis and resistance to treatment.
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A mousetrap for metastases
To block one of the molecular cellular signaling pathways – the trigger for the separation of cancer cells – in other words, to suppress the signal that initiates metastasis, scientists have created a decoy protein.
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Lodamine is the first broad–spectrum angiogenesis inhibitor for oral use
Unlike currently available vascular growth inhibitors, such as Avastin, most of which act only on one of the angiogenesis factors, for example, vascular endothelial growth factor (VEGF) and are approved only for the treatment of a small number of specific types of cancer, Lodamine prevents capillary growth under the action of all tested angiogenesis stimulants.
03 July 2008