31 March 2009

Rapid test will reveal melanoma

A mole from skin cancer can be distinguished by five proteinsA developing melanoma and a benign mole can now be distinguished using an express test for five proteins.

Mohammad Kashani-Sabet and his colleagues from the University of California even managed to work out a new method on the most controversial cases that caused an erroneous diagnosis in 24 patients.

Melanoma developing from skin pigment cells – melanocytes at an early stage can be difficult to distinguish from an ordinary mole or pigment spot. It is even more difficult with self-diagnosis for those who have a lot of such elements on the skin, or for those who develop melanoma from an already existing mole after excessive irritation by the ultraviolet of the sun.

Taking into account the fact that melanoma occupies one of the first places among tumor diseases in terms of malignancy and aggressiveness, and existing treatment methods, including cell therapy, do not give 100% results, the question of early diagnosis is most acute.

The authors of the publication in the Proceedings of the National Academy of Sciences proposed a new method using five tumor marker proteins (ARPC2, FN1, RGS1, SPP1, WNT2) to distinguish melanoma from a mole. After analyzing almost 700 samples, the scientists brought the specificity of their method to 95%, and the sensitivity to 91%, which is very impressive results for oncology.

However, several more years will pass before the introduction into routine clinical practice, and the traditional recommendations of oncologists will remain the same: do not abuse the sun, do not scratch and do not bring moles and age spots to inflammation, and if you have a lot of them, then regularly monitor them.

"Newspaper.Ru»Portal "Eternal youth" www.vechnayamolodost.ru

31.03.2009

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