17 May 2022

Herpes and diabetes

Scientists have found that the herpes virus increases the risk of diabetes by 59%

Svetlana Maslova, Hi-tech+

A long—term study made it possible to identify two types of herpes viruses that increased the likelihood of developing metabolic changes - precursors of type 2 diabetes mellitus. Herpes increases the risks regardless of the presence of excess weight, smoking and indicators of key laboratory biomarkers of health.

Over the past few years, scientists have received convincing evidence of the association of infections with the development of cancer, Alzheimer's disease, multiple sclerosis and other diseases. For example, it is known that 90% of cases of cervical cancer are provoked by the presence of human papillomavirus, and recently scientists have confirmed a direct relationship between Epstein-Barr virus and multiple sclerosis.

Over the past few years, scientists have received convincing evidence of the association of infections with the development of cancer, Alzheimer's disease, multiple sclerosis and other diseases. For example, it is known that 90% of cases of cervical cancer are provoked by the presence of human papillomavirus, and recently scientists have confirmed a direct relationship between Epstein-Barr virus and multiple sclerosis.

In a new study, a team of scientists from Germany sought to assess the impact of various types of herpes virus on the risks of developing type 2 diabetes, the incidence of which is continuously increasing. To date, there are eight known types of herpesviruses that cause latent infections in the body.

Scientists analyzed the data of several thousand people who provided data about their health for about seven years.

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Article by Woelfle et al. Health impact of seven herpesviruses on (pre)diabetes incident and HbA1c: results from the KORA cohort published in the journal Diabetologia – VM.

It turned out that the condition of prediabetes most often developed in people infected with the herpes simplex virus of the second type and cytomegalovirus. In the first case, the risks were 59% higher, and in the second by 33%.

It is noteworthy that these two viruses increased the likelihood of prediabetes regardless of age, body mass index, education level, smoking status, physical activity, hypertension, the presence of diabetes in parents, as well as indicators of insulin resistance and glucose levels.

While scientists do not know the exact mechanism of action of the virus. It probably alters the immune response so that it has a negative effect on the endocrine system, they suggest, but this hypothesis has yet to be studied.

It is possible that the discovery may lead to new methods of treating diabetes. For example, scientists have previously shown that an attack on the Epstein-Barr virus reverses the symptoms of multiple sclerosis in humans.

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