Chemotherapy + diet
The effect of chemotherapy can be enhanced with a diet
Svetlana Maslova, Hi-tech+
Scientists have shown that a ketogenic diet alters the metabolism of cancer and its response to chemotherapy drugs, making the tumor more vulnerable. Currently, clinical studies are continuing to study such nutrition in patients with pancreatic cancer — one of the most deadly types of tumors with a survival rate of less than 10% for five years.
A group of scientists from the USA and China presented the results of preclinical studies of the effect of ketogenic diet on pancreatic cancer. They have shown that this type of diet — low in carbohydrates and proteins and high in fat intake — helps to enhance the effect of chemotherapy and kill cancer cells faster, it is reported on the website of the Translational Genomics Research Institute.
Article by Yang et al. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth published in the journal Med – VM.
Experiments have shown that the ketogenic diet reduced glucose levels in tumors, forcing them to starve. Nutrition also provoked an increase in the level of ketone bodies, which created an additional burden on cancer cells. Among other things, the diet enhanced antitumor immunity by increasing the expression of pro-inflammatory tumor genes.
In 2020, clinical studies were launched to study the effects of the ketogenic diet in patients with pancreatic tumors living in different cities of the United States. Scientists carefully monitor the diet of volunteers and monitor their well-being. The main goal is to assess long-term survival. Currently, it is less than 10% for five years. It is planned that the recruitment of volunteers will continue until the end of 2023. Perhaps scientists will present interim results of observations in the near future.
Studies show that diet correction is useful for various diseases. For example, a diet reduces cholesterol levels no worse than statins, reduces the risk of mortality in Parkinson's disease, treats migraines, protects against dementia, etc.
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