14 June 2024

Bariatric surgery has been found to be most effective for weight loss and weight maintenance

A systematic review of 47 studies presented at the annual scientific conference of the American Society for Metabolic and Bariatric Surgery found that bariatric surgery provides the greatest and most sustained weight loss compared to the use of glucagon-like peptide-1 (GTP-1) receptor agonists and lifestyle modification. According to a team of authors led by New York University's Megan Jenkins, who analysed the medical literature from 2020 to 2024, bariatric procedures lead to an average weight loss of 30 per cent on average and 25 per cent after eight to ten years.

Meanwhile, the researchers found that lifestyle changes - diet and physical activity - lead to an average weight loss of 7.4 per cent, but weight regained within 4.1 years. The GPP-1 agonists were more effective: five months of weekly injections of semaglutide led to a 10.6 per cent weight loss, while nine months of tirzepatide led to a 21.1 per cent weight loss. However, once treatment was discontinued, about half of the lost weight returned within a year. Therefore, the authors conclude that in terms of weight loss effectiveness and weight maintenance, bariatric treatment may be considered the most appropriate.

Found a typo? Select it and press ctrl + enter Print version