Prostate cancer will be determined by biomarkers
A new simple test in 20 minutes and with 100% accuracy will indicate prostate cancer
Svetlana Maslova, Hi-tech+
Korean scientists have developed a test that will report the presence of a suspected tumor in 20 minutes.
Article by Kim et al. Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis is published in the journal ACS Nano – VM.
Until now, when men are suspected of prostate cancer, they perform a blood test, the accuracy of which is only 20-30%. If the result is positive, then an invasive biopsy procedure is prescribed, which increases the risks of side effects. The new test will be effective not only for accurate diagnosis of prostate cancer, but also for other tumors, the researchers said.
Currently, many men undergo an unnecessary biopsy procedure, since a blood test for PSA (prostate-specific antigen) gave a false positive result for cancer. Often the situation is reversed and already with a developing tumor, the test gives a low probability of cancer (a low level of total PSA is determined).
Scientists from The Korean Institute of Science and Technology sought to simplify the diagnosis and make it accurate. They have developed an ultra-sensitive biosensor that uses AI to detect several cancer biomarkers in a urine sample.
The new test will detect cancer in 20 minutes with almost 100% accuracy, writes EurekAlert.
Until now, urine analysis has been used only to assess risk groups for prostate cancer, but scientists have managed to develop an ultra-sensitive device that captures the four most informative factors of a suspected tumor.
The biosensor works on the basis of artificial intelligence, which has been trained to measure traces of selected biomarkers in urine. The accuracy of the test was tested on 76 urine samples from patients with an established diagnosis.
The accuracy was more than 99%, the scientists said, and only a small amount of biomaterial is needed to perform diagnostics.
The introduction of such a test will reduce the number of unnecessary instrumental studies and increase the accuracy of the diagnosis of tumor cancer at an early stage, scientists are sure.
"Our biosensor can be adapted to diagnose other types of cancer by urinalysis," said study author Kwang Hee Lee. However, scientists have not yet reported the expected timing of adaptation of the new test for other oncological diseases.
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