19 July 2017

Tomatoes protected mice from skin cancer

But only males

Anna Kerman, XX2 century, according to the materials of MedicalNewsToday: Daily tomato consumption may protect against skin cancer

A diet with the addition of tomatoes reduced the likelihood of developing skin cancer in mice by 50%. This is the conclusion reached by the authors of a new study conducted on the basis of Ohio State University (Ohio State University). The work has shown how changing the diet can help in managing the risks of developing cancer.

The results of the study – the work was conducted under the guidance of Professor of Pathology Tatiana Oberyshin (Tatiana Oberyszyn) – were published in the publication Scientific Reports (Cooperstone et al., Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations).

Solar radiation falling on unprotected skin is a serious risk factor for cancer. Especially common are the so-called "basal cell carcinomas" that appear from malignated keratinocytes. The risk of death in people with this diagnosis is relatively low, but the total cost of treating patients with basal cell carcinoma in the United States is $ 8.1 billion per year.

Previous studies have shown that eating tomato paste can reduce sunburn. Researchers have linked the protective effect of tomatoes with carotenoids, substances that give tomatoes a red color. Carotenoids enter the skin after eating tomatoes and, apparently, protect against burns. Other scientists have found that the carotenoid lycopene is more effective if you eat tomatoes rather than processed products.

Earlier we have already written about the oncoprotective effect of various products. And as part of the new work, the researchers decided to find out whether the consumption of red tomatoes can significantly reduce the risk of developing malignant skin tumors in mice of both sexes exposed to constant exposure to ultraviolet light. After the experiment, it turned out that the frequency of tumor development did not differ in females from the control and experimental groups. But male mice whose food for 35 weeks consisted of 10% tomato powder suffered from skin cancer 50% less often than mice who did not receive tomatoes at all.

The detected difference between the sexes may be explained by the fact that tumors associated with ultraviolet radiation develop faster in male mice. In addition, in males, such neoplasms are usually larger, more aggressive and easier to metastasize. Thus, according to Professor Oberishin, the study also showed that when developing cancer prevention strategies, it is necessary to take into account gender differences: "What works for men may not suit women and vice versa."

Currently, researchers are working on the following project, trying to determine whether other compounds included in tomatoes have an oncoprotective effect.

Portal "Eternal youth" http://vechnayamolodost.ru  19.07.2017

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