Viruses against melanoma
The herpes virus has saved the lives of dozens of people with incurable melanoma
Gene therapy based on the herpes virus saved the lives of several dozen patients with incurable skin cancer after its approval and the beginning of its use in clinical practice in 2015. Doctors write about this in the journal JACS (Louie et al., Real World Outcomes of Talimogene Laherparepvec Therapy: A Multi-Institutional Experience).
"We have shown that the effectiveness of this therapy in real "combat" conditions is not inferior to what was obtained during clinical trials. We have literally been transported to a new world, because now we can not just massively kill both cancer and healthy cells with chemotherapy, but also force the immune system to attack only the tumor," said David Ollila from the University of North Carolina at Chapel Hill (in a press release from the American College of Surgeons Study Findings Support Genetically Modified Virus Injection into Tumor as a Valid Treatment for Metastatic Melanoma – VM).
In recent years, molecular biologists and physicians have begun to pin special hopes on the so-called immunotherapy in the fight against cancer, allergies, diabetes and other incurable diseases. It is very simple in its essence – scientists are trying to "incite" human immunity to cancer cells using various antibodies, live microbes and a number of other unusual "baits".
One of the most promising methods of fighting cancer in this way have become special genetically modified viruses that can penetrate cancer cells, weaken them or even force them to self-destruct. They have a number of unique advantages – they can be injected into non-operated tumors and they do not touch healthy cells, since they are not able to divide inside them.
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