20 February 2017

Russian scientists presented their new developments

Copper news

A new device for the diagnosis of oncological diseases has been created in Russia. A system called "Biochip" it can determine whether a tumor is malignant much faster than standard diagnostic methods. The analyzer can also be used in a polyclinic, and the patient will be able to receive a primary diagnosis after the first visit.

The work on the device is being carried out by a team of scientists from the N.N. Blokhin Russian Cancer Research Center (RSC), the Nizhny Novgorod Medical Academy and the I.N. Blokhina Institute of Epidemiology and Microbiology. The test system consists of three components – a substrate with 15 cells, each of which contains certain antibodies, as well as fluorescent cells reacting to a chemical reaction, a scanner and a container for storing biomaterial, which contains a special nutrient medium with preservatives. Thanks to this medium, a puncture sample or pathological fluid can be stored in a container for up to a month without special conditions.

Biological samples should be scrolled in a standard medical centrifuge, and then a part of the biomaterial should be placed in each of the cells. During heating up to 37 degrees, chemical reactions of antibodies with tumor antigens begin to occur in the cells, and if the system detects cancer–affected cells, the desired cell will glow due to fluorescent cells. It takes very little time for the reactions to take place, the cost of the examination is not too high – according to these parameters, the biochip wins over existing systems.

The analyzer has already been registered in Russia, and the development will also be transferred under the contract to the countries of the Asia-Pacific region. Small-scale production works in Nizhny Novgorod, and the conclusion of Roszdravnadzor is not enough until the analyzer is launched "to the masses". The creators of the device claim that in April 2017, it will be possible to start supplying polyclinics with biochips.

Another analyzer was created at the Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences in Pushchino. With its help, it will be possible to diagnose tuberculosis in a patient at the earliest possible time by examining his pulmonary fluid obtained noninvasively. During the study, patients breathed into the tube of an electrostatic collector, and small particles of pulmonary fluid, passing around a tungsten charged needle, also received an electric charge, and then thanks to it moved to a graphite substrate. This substrate could be examined using an atomic force microscope and various characteristics of microdrops could be measured. Now the institute's staff is identifying tuberculosis biomarkers in individual microdrops, and if this stage ends with success, it will be possible to talk about creating new equipment for early diagnosis.

Two more studies reported by Russian scientists concerned a new way to measure stress levels, as well as the successful slowing of aging in mice. Stress, as it turned out, affects the composition of human hair, and by measuring the level of the stress hormone cortisol in the hair, you can assess how much the owner is worried and worried. The technique was tested on 20 women who were diagnosed with depression, and, indeed, the lowest level of cortisol was in patients whose condition was the worst. In the course of the second scientific work, scientists significantly slowed down aging in transgenic mice by adding to their diet the antioxidant molecule SkQ1, previously discovered by the same scientific group. The life expectancy of the animals increased by 15%, and they remained healthy longer.

Portal "Eternal youth" http://vechnayamolodost.ru  20.02.2017


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