10 June 2019

Cultural environment in the stationery store

Media: in Japan, they were able to grow stem cells in ordinary glue

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A group of Japanese scientists from the University of Tokyo and the Riken Institute of Natural Sciences have discovered that ordinary glue can be used as a medium for growing stem cells. According to the Asahi Shimbun newspaper, a cheap substitute will significantly reduce the cost of this procedure.

During the study, Japanese biologists tried to create conditions for the cultivation of hemocytoblasts, a type of stem cells from which leukocytes and erythrocytes are formed. For their cultivation, a special liquid is used, the price of which is several hundred dollars per 500 ml of solution. The high cost of the process affects the cost of hemocytoblasts, which is why many patients have to look for a budget alternative, such as bone marrow transplantation.

During the experiments, the scientists placed stem cells in a compound based on polyvinyl alcohol (PVA). The cells showed a 100-fold increase in their population. Then the biologists repeated the procedure, using ordinary glue bought at a stationery store. The result was successful again.

"I felt a real epiphany, like any scientist in my place," said study co–author Yukio Nakamura. According to him, he was "so amazed that he could not believe his own discovery." Now the researchers will test whether the glue is suitable for growing stem cells on a large scale. Another success promises to increase the availability of treatment, as well as reduce the need for bone marrow donors. "Our discovery can make a huge contribution to the development of regenerative medicine," Nakamura sums up.

Article by Wilkinson et al. Long-term ex vivo haematopoietic-stem-cell expansion allows unconditioned transplantation published in the journal Nature – VM.

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