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Is the FOXG1 gene the cause of autism?
By regulating the expression level of FOXG1, the researchers were able to prevent the overproduction of inhibitory neurons from the patient's cells, and also found a link between changes in the expression of this gene and the severity of macrocephaly and autism.
20 July 2015 -
Picking up the keys to pluripotence
A group of scientists from the University of Michigan has shown that the ASF1A and OCT4 genes active in human eggs, together with the hormone-like substance GDF9, facilitate the process of reprogramming somatic cells into pluripotent ones.
01 September 2014 -
iPSCs and cancer cells are similar at the molecular level
This is the first study that describes specific molecular pathways common to induced pluripotent and cancer cells, when compared directly.
05 October 2012 -
Biologists have found problems in pretending cells
Induced pluripotent stem cells retain a genetic memory of their origin. This problem has been solved in mouse iPSCs, but reprogrammed human cells are not yet amenable to attempts to make them forget what they were before.
11 February 2011 -
Complete epigenome
At the next stage, the researchers plan to study the influence of the epigenetic structure of DNA on cell development and the formation of a number of diseases, as well as to evaluate changes in the epigenome during aging and under the influence of environmental factors.
16 October 2009