Hemophilia gene therapy: the first success
After gene therapy, the frequency of spontaneous bleeding in patients with severe hemophilia B decreased by 90%, and the frequency of use of the blood clotting factor IX drug decreased by 92%.
20.11.2014After gene therapy, the frequency of spontaneous bleeding in patients with severe hemophilia B decreased by 90%, and the frequency of use of the blood clotting factor IX drug decreased by 92%.
20.11.2014Biophysicist Maxim Frank-Kamenetsky – about genome editing methods, CRISPR/Cas system and its application in medicine.
14.11.2014By changing the genome of E. coli, American scientists have managed to turn bacteria into analog storage devices.
14.11.2014Previously, when patients were diagnosed with cancer, it seemed like a miracle to overcome the disease. But even today, medicine can safely resist the disease using a powerful weapon – gene therapy.
06.11.2014Stem cells encapsulated in a biodegradable gel synthesizing cytotoxins help to kill brain cancer cells in the cavity left after its resection.
27.10.2014Under the terms of the moratorium, all state bodies of the country stop funding any research to enhance the tolerability and potency of pathogenic microorganisms.
20.10.2014In the 90s, after genetic therapy of X-linked severe combined immunodeficiency, 25% of patients developed leukemia. This time, a viral vector that does not interact with oncogenes was used.
10.10.2014Antibiotics have two problems: non-specificity and antibiotic resistance. Both of these problems will be solved in one fell swoop by the approach proposed by the American-French group of scientists in the journal Nature Biotechnology.
07.10.2014Researchers from MTI have made two substitutions in the FOXP2 gene responsible for human speech, making it from mouse to human. The "humanized" mice have not learned to speak, but they have become smarter than their fellows.
16.09.2014The first transgenic plants reduced the costs of producers, but consumers did not notice the effect. The situation should change soon.
03.09.2014Scientists in Nebraska have embedded foreign amino acids into HIV, which are found in nature only in very rare bacteria, and are going to inject this unnatural virus into mice, and in the future even humans, as a vaccine.
28.08.2014In order for yeast to produce opioids, scientists added five genes to their genome: three from the genome of the poppy, and two more from bacteria that live on poppy plantations.
26.08.2014Gene therapy has taken a step towards the treatment of beta-thalassemia and other diseases caused by a mutation in a single gene. Scientists obtained iPSCs from the patient's cells, edited their genome and forced them to differentiate into blood cells.
19.08.2014A modified version of Clostridium novyi bacteria has a strong and highly specific antitumor effect when administered to mice, dogs and humans.
18.08.2014The minimally invasive gene therapy approach makes it possible to transform non-specialized cardiomyocytes into cells that generate electrical impulses necessary to maintain rhythmic contraction of the heart muscle.
18.07.2014The creators of non-intoxicating nematodes hope to develop a drug that appears in James Bond films and allows you to drink without getting drunk. The same tool will help to remove not only intoxication, but also alcohol dependence.
17.07.2014The use of the most popular gene modification techniques does not increase the number of mutations occurring in stem cells.
11.07.2014Chinyu and Camila became the founders of two lines of transgenic goats. They have already had offspring who have successfully inherited the ability to produce human protein important for hematopoiesis.
10.07.2014E. coli bacteria synthesizing signaling molecules that are formed in the intestine after eating can prevent the development of obesity in mice and even reverse it.
26.06.2014Genetically modified bananas enriched with provitamin A will undergo a clinical trial in the USA.
17.06.2014You can write to the editor at:
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