24 December 2014

Diabetes by blood group

The risk of developing diabetes was associated with blood type

Medical News Today: Type 2 diabetes risk may be influenced by blood typeFrench scientists have found that people with the first blood group are at minimal risk of developing type 2 diabetes mellitus (DM-2).

The results of this work are published in the journal Diabetologia (Fagherazzi et al., ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study).

In a study conducted at the Gustav Russi Institute, data from 82,104 women were examined, which showed that people with the first blood type (0) have a minimal risk of developing diabetes. Compared with women with the first blood group, women with the second group (A) were 10 percent more likely to develop type 2 diabetes, and with the third group (B) – by 21 percent. The data also showed that women with the fourth blood group (AB) were 17 percent more likely to develop type 2 diabetes, but this result was not statistically significant.

Then the scientists analyzed how the Rh factor (Rh) can influence this risk. As it turned out, this protein itself does not affect the risk of DM-2. However, when the researchers examined the relationship between the risk of DM-2 and blood groups together with Rh factor, it turned out that people with the third blood group (B) and Rh factor positive (Rh+) had a 35 percent higher risk of type 2 diabetes compared to a universal donor of the first group with Rh negative-factor (0–).

"Our data confirm the close relationship between blood type and diabetes risk. The data obtained will help in future clinical and epidemiological studies on diabetes. It is also necessary to conduct pathophysiological studies to determine why people with the first blood group have the lowest risk of developing type 2 diabetes," Guy Fagherazzi, the main author of the study, was quoted by Medical News Today as saying.

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