25 September 2014

Take care of your waist from a young age

Extra centimeters in the waist significantly increase the risk of breast cancer

Copper newsThe accumulation of fat deposits in the waist area during life is directly associated with an increased risk of breast cancer after menopause, British researchers have found.

Statistical analysis showed that the intensity of skirt size growth in the period from 25 to 55 years is a clear indicator of the risk of developing the disease at an older age: an increase in waist circumference every ten years by a size increases this probability by 33 percent, and by two sizes – by 77 percent. The work was published in the journal BMJ Open: Fourkala et al., Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).


Graph from an article in BMJ Open – VM

The authors drew their conclusions based on data obtained during a large-scale observational (observational) study of the health of British women, in which from 2005 to 2010 almost 93 thousand post-menopausal women over 50 years old who did not suffer from breast cancer at the start of the study took part. During the monitoring, participants regularly provided detailed information about themselves, including data on body mass index, reproductive health, fertility, family history of breast or ovarian cancer, use of hormonal contraceptives and hormone replacement therapy, lifestyle, smoking and alcohol consumption. All these factors, as previously established, affect the risk of developing breast cancer. In addition, the women indicated their current skirt size, as well as what it was in their youth when they were 20-25 years old.

During the follow-up period, 1,090 participants were diagnosed with breast cancer. Infertility treatment, heredity and the use of hormone replacement therapy turned out to be factors of increased risk of such a development of events, as expected by the researchers. But after all the other factors involved were taken into account, the most clear indicator of the risk of developing the disease in post-menopause was precisely the increase in the size of the skirt during life. The analysis showed that an increase in waist circumference during each decade by a size is associated with a 33 percent, and by two sizes - with a 77 percent increase in the likelihood of breast cancer diagnosis in old age.

Since we are talking about an observational study, the authors do not draw any definite conclusions about the causes of the identified phenomenon. "The biological mechanism underlying this relationship has yet to be established," the researchers note. Nevertheless, they point out, it is known that fat deposits in the waist area, the so-called abdominal fat, are more metabolically active than adipose tissue located in other parts of the body. Abdominal fat contributes to an increase in the levels of the female sex hormone estrogen, which activates malignant processes in the tissues of the mammary glands.

Portal "Eternal youth" http://vechnayamolodost.ru25.09.2014

Found a typo? Select it and press ctrl + enter Print version