13 November 2017

Phosphates should be in moderation

Phosphates are necessary for the normal functioning of the body, they regulate the important process of delivery of oxygen by red blood cells to tissues.

A group of scientists from the University of Surrey (Guildford, UK), in a new study found that insufficient levels of phosphates in blood plasma increases the risk of cardiovascular diseases. This conclusion contradicts the results of previous studies, which proved that a low level of salts in the blood is good for the heart.

In a cohort retrospective study, data from more than 100,000 patients observed by UK general practitioners were selected. The level of phosphates was determined in their blood. The estimated outcomes were acute myocardial infarction, coronary heart disease and vascular heart surgery that occurred 5 and 9 years after the date of the blood test.

It was found that at a low level of phosphates (less than 0.75 mmol/l) the risk of an unfavorable outcome was as high as with a high content of phosphate in the blood (more than 1.5 mmol/l). At an average level (1-1.25 mmol/l) the risk of cardiovascular diseases was the lowest.

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Graph from an article in PLOS ONE

In previous studies, it was proved that a high content of phosphates in the blood increases the risk of vascular pathology of the heart, but now we can say that a lack of phosphates in the blood is also dangerous.

According to the authors of the article, primary care physicians need to keep in mind that another risk factor for heart attack and ischemic disease is a low level of phosphates in the blood.

They write about the need to further study the effect of phosphates on the cardiovascular system, as well as to clarify the mechanisms of this process.

Article by Nicholas Hayward et al. U-shaped relationship between serum phosphate and cardiovascular risk: A retrospective cohort study published in the journal PLOS ONE.

Aminat Adzhieva, portal "Eternal Youth" http://vechnayamolodost.ru based on materials from the University Of Surrey: Heart attacks are more likely in those with low blood phosphate levels.


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